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Most skin cancers are highly curable, but require surgery that can be painful and scarring. A new study by Loyola University Health System researchers could lead to alternative treatments that would shrink skin cancer tumors with drugs. The drugs would work by turning on a gene that prevents skin cells from becoming cancerous, said senior author Mitchell Denning, Ph.D. The study was published Jan. 15, 2010 in the Journal of Biological Chemistry. More than 1 million people in the United States are diagnosed with skin cancer each year. In the new study, researchers examined a type of skin cancer, called squamous cell carcinoma, that accounts for between 200,000 and 300,000 new cases per year. Squamous cell carcinoma begins in the upper part of the epidermis, the top layer of the skin.
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